产品货号:
Z23507
中文名称:
PIWIL2抗体
英文名称:
Anti-PIWIL2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PIWIL2 Antibody |
指标别名 | Cancer/testis antigen 80;CT80;HILI;mili;piwi like 2 (Drosophila);Piwi like protein 2;PIWIL1L;PIWIL2 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | PIWIL2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | PIWI-L2 antibody was raised against a 17 amino acid synthetic peptide near the center of human PIWI-L2.The immunogen is located within amino acids 410 - 460 of PIWI-L2. |
计算分子量 | 110kDa |
成分 | PIWI-L2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | PIWI-L2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | PIWI-L2 is a member of the PIWI subfamily of Argonaute proteins,evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal,RNA silencing,and translational regulation in diverse organisms.PIWI-L2 has been implicated in multiple roles including stem cell self-renewal and is highly expressed in many breast cancers.In these tumors,PIWI-L2 silences the expression of STAT3,a regulator of Bcl-XL and cyclin D1,allowing the proliferation and survival of breast cancer stem cells.Recent studies have shown that overexpression of PIWI-like proteins are potential biomarkers for colon and other cancers. |
Uniprot ID | Q8TC59 |
基因名全称 | Piwi-like 2 |
蛋白名全称 | Piwi-like 2 |
推荐稀释比 | PIWI-L2 antibody can be used for detection of PIWI-L2 by Western blot at 1μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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